Extensive maxillary lesions: Refer this out due to potential malignancy?

I have just examined a new patient whose chief complaint is that he wants all his maxillary teeth extracted and replaced with implants. He presents with extensive severe chronic aggressive adult periodontal disease with very mobile maxillary teeth. A CBCT scan revealed bilateral extensive maxillary lesions, which initially appear to be caused by aggressive perio. I am considering extracting all the maxillary teeth and doing a biopsy and then possibly doing guided bone regeneration and installing implants. The patient was a heavy smoker, but stopped one year ago. Rest of perio is under control (excluding affected regions). I am more than competent and willing to extract teeth and carry-out biopsy on lesions but concerned if there is malignancy LHS (which I doubt), would I be putting patient at risk? Also, should GBR be considered? Should I proceed on my own or refer out?


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21 Comments on Extensive maxillary lesions: Refer this out due to potential malignancy?

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CRS
1/6/2014
If it were me I would stage it, remove teeth send off the questionable areas for biopsy, periolase the graft beds and do a conservative graft with primary closure. Then I would see what kind of base bone you get. I think this patient would benefit with locators in the canine and second premolar areas. Once the mouth us cleaned up go from there.
DrG
1/7/2014
Honestly this requires little thought. If you're asking yourself the question you already know the answer. That lesion in the maxillary left is concerning. As CRS said the starting point is cleanup, send the patient to a board certified OS with hospital privileges. Get all the teeth out, let it heal. If it's not cancer, then smoking cessation, sinus lifts, ridge augmentation and later implants.
Dr Bill
1/7/2014
Is that a pan or is it reformatted from your conebeam? the images on the pan look different than the segments. If the segments are from a pan the lesions look very aggressive with root resorption, but if a reformat this could just be the slice thickness. I think it would be odd to have a bilateral aggressive lesions that are not perio related but could have 2 different things going on. I would check for diabetes on this patient or a family HX of this. Smoker? You don't need a surgeon to take these out you just have to be able to clean it up and evaluate what you find. Let the soft tissue heal then go back and do grafts so you can get full closure and also see how the tissue heals You better plan the occlusion out-locators at the cuspid and bi's is a short term failure- you don't have enough posterior support to protect the implants from lateral forces. You need 6-8 and you really need to evaluate how you are going to protect the implants and give him more that bicuspid occlusion-jmho
DrG
1/7/2014
Let me propose the following scenario (since obviously Dr Bill has never encountered this) you extract tooth 15 and begin curretting the bone posterior to it. Next thing you realize this bone doesn't feel like bone, it's more like styrofoam. What now? Stop? If you keep going it obvious your into the sinus and maybe the floor of the orbit. So you stop. The problem is cancer doesn't heal like infected tissue. Now, if the patient survives his next year of aggressive resection, chemo and radiation he will probably wear some sort of crazy obturator because your surgery didn't heal well. This is beyond most doctors training, certainly general dentists. (Yes I said it). The amount of training and experience a resident gets at Mass General or the center for head and neck cancer in New York is so extensive it frightens me to think anyone would touch that lesion without at least a consultation from an expert.
Dr Bill
1/8/2014
Obviously you are an esteemed oral surgeon and your scenario is possible. What would be your procedure here ? Do you take the teeth out and do respective surgery if the tissue feels like foam at that appointment or do you send off for a biopsy to see what you have as the tissue heals? Is it more appropriate to do respective surgery in the presence of possible infection or wait until you have a dx from biopsy? Do you make the cancer ? More aggressive by removing infected teeth or can you better manage the area when the inflammation from the PD disease and tooth related infection is controlled? Certainly you will be better able to do cancer surgery than most GPs but I fail to see how you would do the preliminary extractions and Dx any different than a general dentist and there would be probably less time delay. It usually takes 3-4 weeks to get a patient to an OS where most dentist can have these out sooner and on the way to a Dx and alerting the OS of what is coming IMHO
michaelwjohnson dds, ms
1/7/2014
wow, what a mess. This needs to be in the hands of an oral surgeon. And a prosthodontist. You might be OK to remove teeth but 1) what if it's cancer? 2) what if it's not? What's your restorative plan? With all due respect to CRS but four locators is a very poor way to restore a fully edentulous maxilla. The locators will all flare with the flare of the maxilla so they won't have a common path of insertion. They aren't splinted and, in this patients poor bone, they will fail. There's no bone in the posterior regions so are you going to do an onlay graft? A sinus inlay graft? Are you making an overdenture? Fixed restoration? Ceramometal or acrylic hybrid? Like Dr. Bill said, you need 6-8 implants, splinted together, to treat this patient properly and that will require extensive bone augmentation. As you can see, the edentulous implant patient isn't simply "take out the teeth, slam in a couple of locators and make a denture". It requires careful planning and surgical and restorative skill. Add in the question of cancer and you shouldn't be treating this patient.
LuizNameL
1/8/2014
We face an aggressive bone resorption caused by severe periodontal disease where nothing and can do to keep the maxillary teeth. I would make the tooth extraction and would wait two to four months, then do the rehabilitation.
CRS
1/8/2014
Actually what would be very helpful would be a clinical photo since oral cancer does not usually present in this manner. The lesions are exophytic and bone destruction is a later finding or a metastatic process. Oral cancer does spread locally and can invade bone. But all this is conjecture until a tissue diagnosis is made. This patient would get better care in the hands of a skilled OMS who can manage pathology, sinus invasion, and other complications from the surgery. And I might add primary closure. I stated the locators since thus patient needs to be able to handle simple hygiene first, and it is a very simple concept to place four parallel drawing locators for a tissue borne implant retained prosthesis, it works quite well. Yes I said it a prudent dentist would refer this to an OMS and put the patient welfare first. I have had much experience with general dentists, periodontists etc treating these cases and having to treat the problems or sequela afterwards, whatever rationale given, time, convenience, costs are just that rationale to justify taking on a case for whatever reason. Some of the posts on this blog show how little knowledge,skill and experience is prevalent in oral and maxillofacial surgery. This can't be obtained in a weekend course or a fancy gadget. I respect what my dental colleagues can do in their fields and work with them as colleagues. I don't tell them how to restore they should know that. Actually complications and poor treatment of these cases will drive to patient away with a poor experience for the patient. I 'm very sorry if I offend dentists but sometime an honest opinion is better than trying to make a referring dentist feel better. My concern is for the patient who has been entrusted to us. General dentistry, implantology, perio etc are difficult enough when done well not to mention Oral Surgery where the buck usually stops. There are many practitioners who wisely get this, and there are those who have sleepless nights. I only share what I have seen and post because I do care no one is perfect myself included. Thank you for reading I know I will get criticized for this but I feel that it was necessary to address the elephant in the living room.
Dr Bill
1/8/2014
Wow! this IS a conversation we in dentistry need to have- first let me say that if you look at the individual images vs the pan they don't appear to be from the same picture and if you are saying that the cloudy nature of the lesion on the left side of the side slice is disconcerting what about the cloudy nature above the bicuspids on the right slice . I think this is about the conebeam reformatting and these are not diagnostic or a true radiographic assessment of the areas. second I don't think any Gp is going to explore this region up tho the pts brain and keep going or do I think they would avoid referring this if the find an odd appearance after extraction of the teeth or tissue healing issues. All the problems the pt has that you mentioned will be the result of the extensive surgery to remove the lesion not because the GP took out the teeth and you are not going to be bailing out a dentist here you are going to be doing your job as part of a team. So tell me ,as oral surgeons, I am still waiting for what your first step is here- Im a general dentist - educate me on why you dont take the teeth out first or do you? do you do your biopsy before the extractions, during, or after healing ? How are you going to get primary closure here and why do you want it? When are you going to graft-are you going to graft into these infected sites and then attempt primary closure? Are you going to have a denture made for immediate insertion and if you are what is the dentist to do when you have pulled all of the tissue over for primary closure-- It is easy to discuss the procedures you are going to do but discuss the timing of this Are you going to extract and do the invasive resective surgery at the same appointment if you determine that the consistency of the tissue is odd or will you biopsy at this point and see what turns up? so if there is a funny tissue here will you continue to currette up into the sinus at this appointment before you know what you are dealing with? If it is cancer are they all treated the same or are some irradiated first or treated with chemo to decrease the size or do you just start removing tissue? What happens to the keratinized tissue when you do primary closure and now you send them to me to restore? I get primary closure with a resection but not with extractions that makes no sense to me You've placed implants at the bicuspid and cuspid retained by locators Im not aware of any study that confirms this as a successful procedure in the maxilla. It may be easy to put the implants in, get them parallel and place locators surgically this is a win for you the OS but it is a disaster waiting to happen to the GP that has to restore this -now the patient wants to know why the denture teeth break off or the denture breaks or the implants fail after a few years or the retainers are constantly replaced because the denture keeps getting loose Now the GP has to figure out what he is doing wrong because the implants integrated well,so it must be his fault - you as the OS are off the grid as far as the patient is concerned- the implant planning is all wrong but they integrated and the patient paid all that money and they expect it to work for you the OS to think that this would work in this case shows a lack of knowledge of the dynamics of removable prosthetics, occlusion and occlusal dynamics--This is the elephant in the room- the GP has deferred to the surgeons the decisions about implant placement and the surgeon has given him the answer. The truth is that the success of the case is based on an understanding of the occlusal forces on the prosthesis and the lack of posterior support that is available here-yes this is more about denture dynamics than fixed prosthesis- Put an upper denture in here and you will soon see what the dynamics are going to be on your implants It is easy to point out how you bail out the GPS and Periodontist for the things that show up in your office but Gps have been bailing out OS since implants were first placed It is the astute OS that learns the dynamics of the occlusion and treatment planning and the force dynamics that contribute to implant loss What I see is that surgeons understand surgery, GP understand restorative but we don't know as a collective group the dynamics of the systems when combined with implants- you can't understand this in a weekend course-When was the last time your surgeon attended a course on implant treatment planning and occlusion The more I learn about implants the more I see I don't know IMHO
CRS
1/8/2014
Dr Bill my cases are treatment planned per the restorative doctor as it is restoratively driven surgery. My prostodontist likes four locators when appropriate in the maxilla, it is his call. Your questions were answered in my first post. I have attended many restorative courses but I still rely on my restorative colleague as he trusts me to perform the surgery per my judgement. I think you may be overthinking the process. I get very nice results I'm sorry that you have had such difficulties with your team. Funny but I treat you guys like the quarterback and I welcome the feedback, just hope you can hear my feedback. Perhaps the problem lies on the working relationships between team members. I know enough about occlusion and prosthetics to get into trouble so I respect my restoring doctor as he respects what I do and trusts it. Thanks for the comments!
michaelwjohnson dds, ms
1/8/2014
Dr. Bill, Thank you for your comment! I'm glad you discussed that surgeons should not be discussing prosthodontic care any more than I, as a prosthodontist, should be discussing bone grafting materials or other surgical specifics. I agree with you that four locators makes no sense. When evaluating the other posters comments he stated that four locators is a simple solution until the patient improves his hygiene. Why would anyone place four implants as a simple solution I(it's not a simple solution) and see if it works? what if it doesn't work (which it probably won't)? Then the patient is out time and money and, per the other poster, was given poor treatment advise and the patient in turn gets frustrated. Per the poster, I'm sorry to offend anyone, but let's treat this patient rationally. How about removing the teeth, debriding the area, biopsing if needed then making a temporary denture. Let the surgical site heal then reevaluate the patients home care and motivation before jumping into expensive treatment. If the patient is doing fine with a denture then simply make a final denture after six months of healing. If the patient still wants implants then a more definitive treatment plan can be developed, involving the surgeon in the discussion of where and how much bone to graft with restorative input on implant positioning. Place enough implants (4 widely spaced or 6-8 evenly spaced) to support and retain a final prosthesis and make sure the implants are splinted to spread out occlusal forces. There is nothing wrong with going slowly with these complicated cases.
CRS
1/8/2014
Ditto, well said much more tactful than me!
Dr Bill
1/9/2014
perfect!
osurg
1/9/2014
I think the question of what to do depends on what you are dealing with. Presented with this patient I would take one or two representative tissue samples for pathology limiting my treatment to making a diagnosis and not doing much more. In 48-72 hours I would have the answer as to what this is and then make a treatment plan. As a general dentist if you know how to take an adaquate sample for pathology you should do it. If not then send the case out to an OMS (sorry to use what has become a bad word) we OMS are at times useful inspiteof the tone of ths site.
Dr Bill
1/9/2014
Tying to learn here--would your biopsy contain the root 16? if the biopsy comes out positive for a form of cancer what is your next step? If radiation is on the horizon as part of your the treatment would you have to consider removing the lower teeth also
michaelwjohnson dds, ms
1/9/2014
CRS I always enjoy your surgical input as it broadens my horizons as to surgical care.
CRS
1/11/2014
As I do enjoy learning from your feedback doctor. I had a similar case on an older patient the mucosa was speckled and bleeding and he was a smoker. I biopsied and prepared the patient for the worst. I was very relieved to have a benign diagnosis on the worse case of perio I have ever seen, I still remember the case! My point is that knowing when to refer and having a backup system for the patient's benefit, cost and convenience is my philosophy. There is plenty of dentistry to do out there and I applaud many of these posters for seeing that and use our professional colleagues. It is pretty silly to take offense at surgical advice given by an oral surgeon with a lot of experience and hopefully humility. Sometimes I feel that I am using the "OMS" word! Thank you for your complement, it made my day!
DrG
1/9/2014
Dr Bill, in response to your earlier question of how we proceed with an invasive cancer of the maxilla... Pt has been seen pre-sx he/she is advised of the following sequelae, removal of teeth with local curettage to hemi-maxillectomy. On surgical day pt is anesthetized under general anesthesia, biopsy is taken and submitted for frozen section. Depending on the results we continue to remove lesion until clean margins are noted by the pathologist. Obviously the patients maxillary teeth are removed as well. From there depending on the surgical wound the area us closed. Sometimes we need to use tissue from another area such as the back or buttocks. From there the patient is moved to post op and eventually he will meet with the oncology team who will treatment plan his/her chemo/radiation based on the type of carcinoma. So the next question is, what if it's not cancer? Wonderful, patient walks out with a full arch extraction, possible bilateral sinus grafts, ridge preservation mostly covered by his Medical insurance since it was done in a hospital environment. Patient then can return to the referring dentist for implants/dentures etc.... Hope this answers your questions, happy to explain.
Dr Bill
1/10/2014
That is perfect. Is there any concern working in an area of active infection? It seems to me that this could impact the surgery and increase the risk of post op infection
Richard Hughes, DDS, FAAI
1/11/2014
I agree with biopsy and suggest that a maxillofacial radiologist view the images or take and examine further images. If all ok then move on with augmentation after the infection is under control and implant later. If CA is present stop, refer to an OMS and ENT team. The patient may need a prosthodontist if cancer is present and extensive removal of tissue occurred. Let's fact the facts, the OMS are very well trained to manage cancer patients. One does not learn how to treat cancer patients in implant courses. Again, firstly diagnose then refer if needed.
rsdds
1/14/2014
could it be osteomyelitis ? is there any pus .. some say there's no om in the maxilla because of the vascularity what do you think??

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