Osteogen: When can the implant be placed following socket preservation?

4 to 6 months

Osteogen is calcium sulfate and resorbs very quickly. In one month you will not be able to see it. You need a different type of material so it will remain in the socket longer due to the slow nature of bone formation. Beta tricalcium phosphate may be a better choice for you. You can also mix it with allograft such a dfdb.

we need to rethink about rational behind what we are doing, so thinking about socket preservation must be based on our understanding of socket healing and we either put a material going with this direction then well and good if not then we are wasting precious time, what i want to say is if you have a socket means 4 walls then normally you can reenter this place after 4-6 weeks depend on thickness of left cortical plate.ridge preservation is more important which means defect in buccal wall in this case I prefer to use PRF and reentering accordion to different factors includes pt. age, type of bone and size of defect

Carlos, I have not had that problem with Osteogen. I pack it densely and make sure there is bleeding from the bone. I have had great results with Osteogen.

Osteogen is NOT calcium sulphate. It is a resorbable hydroxyapatite made by Impladent. Kind Regards, Bill Schaeffer

in my experience, one of the best resorbable graft material, is calcium carbonate. particles of a range between 40 micron and 800 micron . it's resorbs in about thirteen months. personally i insert this graft ( biocoral, shepore etc.) in the post extractive soket simultaneously wit the right implant. best regards lex

My mistake, Thanks to Dr. Kurtzman for pointing it out. I confused Osteogen with the Orthogen product DentoGen which is based on medical grade calcium sulfate hemihydrate. Thanks again for the quick correction.

There is an ever-growing interest and development of alloplastic materials leading to some good thinking in the goal of returning the body to healthy host bone. This material is another such move forward in understanding Cap and their benefits but surgical techniques can be important in obtaining the optimal results . Good to see your interest here Bill , hope you are well. Regards Peter

I suggest you contact the company. But my guess is that they will not be able to give an answer because they most likely have never used the product on a patient. Because this is calcium sulfate all the company needs to do is to submit to the FDA that it is calcium sulfate like all of the other calcium sulfates and they get approval without ever using it in a patient. If they want to put in print when you can place an implant then they must show clinical data that the product is fully resorbed but because they have no data the FDA prohibits them from telling you when you can place an implant. So when you look at advertising on various bone grafts and this type of information is missing you will know why. Greg Steiner Steiner Laboratories

...Thank you for keeping me updated. I have biopsied a failed bio-oss graft and I have it well documented. The histology shows organic material. I am in the process of having that sample stained for proteins and I will keep you informed... Schlegel und Donath [25] konnten bei 126 klinischen Biopsaten mit einem Nachsorgezeitraum bis zu sechs Jahren keine Resorptionszeichen nachweisen. BIO-OSS--a resorbable bone substitute? Department of Oral Maxillofacial Surgery, Ludwig Maximilians University, Munich, Germany. Abstract BIO-OSS is an allergen-free bone substitute material of bovine origin, used to fill bone defects or to reconstruct ridge configurations. Seventy one patients (39 female, 32 male) received 126 BIO-OSS implantations. Some health parameters or habits were documented to eliminate possible risk factors of influence. The diameter of jaw defects filled with BIO-OSS was measured. There was a significant influence of the defect size on the healing result. In X-ray controls, BIO-OSS served to identify the surrounding native bone. The density of the BIO-OSS areas was higher than in control sites. These radiological results were supported by bone biopsies. Histologically, the permanency of the BIO-OSS was still recognizable after 6 years and longer. The ingrowth of newly formed bone in the BIO-OSS scaffold explained the increased density of the implanted regions. There were no clinical signs of BIO-OSS resorption. Therefore, we can assume that form corrections achieved by BIO-OSS insertions will last. PMID: 10186966 [PubMed - indexed for MEDLINE]

Agreed Maurice which is good to be able to see the extent of the graft radiographically . Using BTcP and Caso4 our cores samples show less than 15 % of residual graft material at 10 weeks which will be bio-aborbed showing only host bone . So story is depends what you put in and linking such a wide range of materials together and saying they are merely all ceramics of a sort is strange. Peter

Thank you Maurice. Your comments are correct and appreciated.

Dr. U I have also biopsied failed low temperature cow bone and have also found the organic matrix present after demineralization. A biopsy of an older specimen (over 10 years in situ) showed an intact organic matrix. A more recent biopsy (approximately 3 years in situ) showed the organic matrix present but much more degenerated which may be the result of attempting to truly make it anorganic. Blue trichrome staining indicated the presence of proteins. Greg Steiner Steiner Laboratories